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    bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 553529, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bloc1s3provided by ZNC
    Official Full Name
    biogenesis of lysosomal organelles complex-1, subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-10
    See related
    Ensembl:ENSDARG00000068828 AllianceGenome:ZFIN:ZDB-GENE-050913-10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:114034
    Summary
    Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 8. Orthologous to human BLOC1S3 (biogenesis of lysosomal organelles complex 1 subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See bloc1s3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (35082757..35101292, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35236325..35243323, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:ch73-95l15.5 Neighboring gene rho guanine nucleotide exchange factor 28 Neighboring gene tektin like 1 Neighboring gene sestrin 3 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 3 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genetic characterization and in vivo image analysis of novel zebrafish Danio rerio pigment mutants. Hsu CC, et al. J Fish Biol, 2013 May. PMID 23639161
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114034

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    biogenesis of lysosome-related organelles complex 1 subunit 3
    Names
    hps8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025476.1 → NP_001020647.1  biogenesis of lysosome-related organelles complex 1 subunit 3

      See identical proteins and their annotated locations for NP_001020647.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097102
      UniProtKB/TrEMBL
      A0A2R8PY82, A0A8N7XJJ5, F1RA74, Q4V924
      Related
      ENSDARP00000100799.3, ENSDART00000109593.5
      Conserved Domains (1) summary
      pfam15753
      Location:8 → 189
      BLOC1S3; Biogenesis of lysosome-related organelles complex 1 subunit 3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      35082757..35101292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157762.5 → XP_005157819.1  biogenesis of lysosome-related organelles complex 1 subunit 3 isoform X1

      See identical proteins and their annotated locations for XP_005157819.1

      UniProtKB/TrEMBL
      A0A2R8PY82, A0A8N7XJJ5, F1RA74, Q4V924
      Related
      ENSDARP00000090450.4, ENSDART00000099677.5
      Conserved Domains (1) summary
      pfam15753
      Location:8 → 189
      BLOC1S3; Biogenesis of lysosome-related organelles complex 1 subunit 3

    RNA

    1. XR_011006339.1 RNA Sequence

    2. XR_011006342.1 RNA Sequence

    3. XR_011006340.1 RNA Sequence

    4. XR_011006341.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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