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    crcp calcitonin gene-related peptide-receptor component protein [ Danio rerio (zebrafish) ]

    Gene ID: 751656, updated on 9-Dec-2024

    Summary

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    Official Symbol
    crcpprovided by ZNC
    Official Full Name
    calcitonin gene-related peptide-receptor component proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060825-150
    See related
    Ensembl:ENSDARG00000069373 AllianceGenome:ZFIN:ZDB-GENE-060825-150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rcp9; zgc:153737
    Summary
    Predicted to enable nucleotide binding activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is expressed in blastomere and hematopoietic system. Orthologous to human CRCP (CGRP receptor component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See crcp in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (31244274..31252143, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (31207577..31215476, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene tyrosylprotein sulfotransferase 1, like Neighboring gene argininosuccinate lyase Neighboring gene carbonic anhydrase IV c

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish. Wei Y, et al. Development, 2016 Jun 15. PMID 27151951
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153737

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within hematopoietic stem cell homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within hematopoietic stem cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase III promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within transcription initiation at RNA polymerase III promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase III subunit RPC9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045373.2 → NP_001038838.2  DNA-directed RNA polymerase III subunit RPC9

      Status: VALIDATED

      Source sequence(s)
      CR450753, EH585180
      UniProtKB/TrEMBL
      A0A8M1NAV1, F1QK38
      Related
      ENSDARP00000107938.2, ENSDART00000121946.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      31244274..31252143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468909.2 → XP_021324584.1  DNA-directed RNA polymerase III subunit RPC9 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PIF8
      Conserved Domains (1) summary
      pfam03874
      Location:1 → 115
      RNA_pol_Rpb4; RNA polymerase Rpb4
    Nucleotide Protein Strain
    Heading Accession and Version

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