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    mindy3 MINDY lysine 48 deubiquitinase 3 [ Danio rerio (zebrafish) ]

    Gene ID: 777708, updated on 9-Dec-2024

    Summary

    Official Symbol
    mindy3provided by ZNC
    Official Full Name
    MINDY lysine 48 deubiquitinase 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061110-13
    See related
    Ensembl:ENSDARG00000028715 AllianceGenome:ZFIN:ZDB-GENE-061110-13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam188a; fb94a02; wu:fb94a02; wu:fy30f06; zgc:153892
    Summary
    Predicted to enable K48-linked deubiquitinase activity. Predicted to act upstream of or within apoptotic process; protein K48-linked deubiquitination; and proteolysis. Predicted to be located in nucleus. Orthologous to human MINDY3 (MINDY lysine 48 deubiquitinase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mindy3 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (28270024..28371330)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (28335480..28436707)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene GTPase IMAP family member 9-like Neighboring gene si:dkey-12j5.1 Neighboring gene integrin, alpha 8 Neighboring gene family with sequence similarity 171 member A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables K48-linked deubiquitinase activity  
    enables K48-linked deubiquitinase activity  
    enables cysteine-type deubiquitinase activity  
    enables cysteine-type peptidase activity  
    enables hydrolase activity  
    enables peptidase activity  
    Component Evidence Code Pubs
    located_in nucleus  

    General protein information

    Preferred Names
    ubiquitin carboxyl-terminal hydrolase MINDY-3
    Names
    deubiquitinating enzyme MINDY-3
    family with sequence similarity 188, member A
    protein FAM188A
    ubiquitin carboxyl-terminal hydrolase FAM188A
    NP_001071224.1
    XP_068070122.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077756.1 → NP_001071224.1  ubiquitin carboxyl-terminal hydrolase MINDY-3

      See identical proteins and their annotated locations for NP_001071224.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124766
      UniProtKB/Swiss-Prot
      A0AUR5
      Related
      ENSDARP00000059034.6, ENSDART00000059035.7
      Conserved Domains (1) summary
      pfam13898
      Location:29 → 299
      DUF4205; Domain of unknown function (DUF4205)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      28270024..28371330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214021.1 → XP_068070122.1  ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1

      UniProtKB/Swiss-Prot
      A0AUR5
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