aebp1b AE binding protein 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aebp1bprovided by ZNC
Official Full Name: AE binding protein 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8546
See related: Ensembl:ENSDARG00000006901 AllianceGenome:ZFIN:ZDB-GENE-030131-8546
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb14g01; wu:fb14g01; CH1073-459J12.1; si:ch1073-459j12.1
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process; protein processing; and regulation of DNA-templated transcription. Predicted to act upstream of or within proteolysis. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome classic-like 2. Orthologous to human AEBP1 (AE binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (44759567..44800691)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (44765655..44806787)

Chromosome 8 - NC_007119.7

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fb14g01.x1 (e-PCR)
- UniSTS:202931

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables carboxypeptidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
NOT enables metallocarboxypeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables metallocarboxypeptidase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
NOT involved_in peptide metabolic process	IBA Inferred from Biological aspect of Ancestor more info
NOT involved_in protein processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: inactive carboxypeptidase-like protein X2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007119.7 Reference GRCz11 Primary Assembly

Range

44759567..44800691

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_690930.10 → XP_696022.6 inactive carboxypeptidase-like protein X2 isoform X1

UniProtKB/TrEMBL

A0A8N7TEF3, F1RAC0

Related

ENSDARP00000113570.1, ENSDART00000132115.2

Conserved Domains (6) summary

cd11308
Location:1040 → 1115

Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain

smart00231
Location:403 → 556

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

smart00410
Location:62 → 145

IG_like; Immunoglobulin like

cd00057
Location:402 → 555

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

cl11393
Location:577 → 1036

Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

cl11960
Location:56 → 147

Ig; Immunoglobulin domain
XM_005167251.5 → XP_005167308.1 inactive carboxypeptidase-like protein X2 isoform X2

UniProtKB/TrEMBL

A0A8M2BFA8

Conserved Domains (6) summary

cd11308
Location:1039 → 1114

Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain

smart00231
Location:402 → 555

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

smart00410
Location:62 → 145

IG_like; Immunoglobulin like

cd00057
Location:401 → 554

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

cl11393
Location:576 → 1035

Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

cl11960
Location:56 → 147

Ig; Immunoglobulin domain