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    trmt112 tRNA methyltransferase activator subunit 11-2 [ Danio rerio (zebrafish) ]

    Gene ID: 553790, updated on 9-Dec-2024

    Summary

    Official Symbol
    trmt112provided by ZNC
    Official Full Name
    tRNA methyltransferase activator subunit 11-2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-30
    See related
    Ensembl:ENSDARG00000071878 AllianceGenome:ZFIN:ZDB-GENE-050522-30
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110652
    Summary
    Predicted to enable tRNA methyltransferase activator activity. Predicted to be involved in maturation of LSU-rRNA; maturation of SSU-rRNA; and positive regulation of rRNA processing. Predicted to act upstream of or within methylation. Predicted to be part of tRNA (m2G10) methyltransferase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TRMT112 (tRNA methyltransferase activator subunit 11-2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See trmt112 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8806422..8814517, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (8500308..8508403, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily K, member 4a Neighboring gene uncharacterized LOC137487564 Neighboring gene transforming growth factor, beta 5 Neighboring gene autophagy related 2A Neighboring gene nuclear RNA export factor 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC110652

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA methyltransferase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of tRNA (m2G10) methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    multifunctional methyltransferase subunit TRM112-like protein
    Names
    tRNA methyltransferase 11-2 homolog
    tRNA methyltransferase subunit 11-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020752.1NP_001018588.1  multifunctional methyltransferase subunit TRM112-like protein

      See identical proteins and their annotated locations for NP_001018588.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095351
      UniProtKB/TrEMBL
      A0A8M1N6K8, Q503F3
      Related
      ENSDARP00000097448.3, ENSDART00000106670.5
      Conserved Domains (1) summary
      cl01066
      Location:86112
      Trm112p; Trm112p-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      8806422..8814517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394892.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      160483..168578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)