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    dtx2 deltex 2, E3 ubiquitin ligase [ Danio rerio (zebrafish) ]

    Gene ID: 568626, updated on 9-Dec-2024

    Summary

    Official Symbol
    dtx2provided by ZNC
    Official Full Name
    deltex 2, E3 ubiquitin ligaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081022-150
    See related
    Ensembl:ENSDARG00000032933 AllianceGenome:ZFIN:ZDB-GENE-081022-150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:194800
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Orthologous to human DTX2 (deltex E3 ubiquitin ligase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See dtx2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (59553244..59595597)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58883970..58925883)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene CAP-GLY domain containing linker protein 2 Neighboring gene GTF2I repeat domain containing 1 Neighboring gene uncharacterized LOC137495527 Neighboring gene transmembrane protein 132E Neighboring gene uncharacterized LOC137495646

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC194800

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    probable E3 ubiquitin-protein ligase DTX2
    Names
    deltex homolog 2
    deltex2
    NP_001120779.2
    XP_068077382.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127307.2NP_001120779.2  probable E3 ubiquitin-protein ligase DTX2

      Status: VALIDATED

      Source sequence(s)
      BX901917
      UniProtKB/TrEMBL
      B2KJ27
      Related
      ENSDARP00000156536.1, ENSDART00000192345.1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      59553244..59595597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221281.1XP_068077382.1  probable E3 ubiquitin-protein ligase DTX2 isoform X1

      UniProtKB/TrEMBL
      B2KJ27
      Related
      ENSDARP00000139213.1, ENSDART00000169308.2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394620.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      180241..222561
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)