U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    antxr1c ANTXR cell adhesion molecule 1c [ Danio rerio (zebrafish) ]

    Gene ID: 563907, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    antxr1cprovided by ZNC
    Official Full Name
    ANTXR cell adhesion molecule 1cprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090514-5
    See related
    Ensembl:ENSDARG00000063612 AllianceGenome:ZFIN:ZDB-GENE-090514-5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    antxr1
    Summary
    Predicted to enable transmembrane signaling receptor activity. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in cranial vasculature; spinal cord; tail bud; and trunk vasculature. Human ortholog(s) of this gene implicated in GAPO syndrome and colorectal carcinoma. Orthologous to several human genes including ANTXRL (ANTXR like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See antxr1c in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (2677278..2740719)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (2642524..2705622)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene interphotoreceptor retinoid-binding protein like Neighboring gene retinol binding protein 3 Neighboring gene ubiquitin domain containing 1b Neighboring gene MMS19 homolog, cytosolic iron-sulfur assembly component Neighboring gene zinc finger DHHC-type palmitoyltransferase 16b

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Anthrax toxin receptor 2a controls mitotic spindle positioning. Castanon I, et al. Nat Cell Biol, 2013 Jan. PMID 23201782
    2. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Wong KS, et al. Dev Dyn, 2009 Jul. PMID 19504456
    3. Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. Gomez GA, et al. PLoS One, 2009. PMID 19308258, Free PMC Article
    4. Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. Gomez G, et al. PLoS One, 2012. PMID 22438865, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    anthrax toxin receptor 1
    Names
    anthrax toxin receptor 1c
    tem8

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      2677278..2740719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_687270.8 → XP_692362.2  anthrax toxin receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8N7TBB2, E7F2W8
      Related
      ENSDARP00000087545.4, ENSDART00000093113.6
      Conserved Domains (3) summary
      cd01474
      Location:37 → 218
      vWA_ATR; ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis, the causative agent of anthrax. ATR is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells. The VWA domain in ...
      pfam05586
      Location:391 → 483
      Ant_C; Anthrax receptor C-terminus region
      pfam05587
      Location:220 → 314
      Anth_Ig; Anthrax receptor extracellular domain

    2. XM_009306392.4 → XP_009304667.1  anthrax toxin receptor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M3BDY9
      Related
      ENSDARP00000155513.1, ENSDART00000185909.1
      Conserved Domains (3) summary
      cd01474
      Location:37 → 218
      vWA_ATR; ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis, the causative agent of anthrax. ATR is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells. The VWA domain in ...
      pfam05586
      Location:391 → 483
      Ant_C; Anthrax receptor C-terminus region
      pfam05587
      Location:220 → 314
      Anth_Ig; Anthrax receptor extracellular domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.