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    higd1a HIG1 hypoxia inducible domain family, member 1A [ Danio rerio (zebrafish) ]

    Gene ID: 373084, updated on 9-Dec-2024

    Summary

    Official Symbol
    higd1aprovided by ZNC
    Official Full Name
    HIG1 hypoxia inducible domain family, member 1Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030826-15
    See related
    Ensembl:ENSDARG00000022303 AllianceGenome:ZFIN:ZDB-GENE-030826-15
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hig1; cb659; zgc:77692; wu:fb57h02
    Summary
    Predicted to be involved in mitochondrial respirasome assembly. Predicted to be located in membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including axis; gill; musculature system; solid lens vesicle; and spleen. Orthologous to human HIGD1A (HIG1 hypoxia inducible domain family member 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See higd1a in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2168547..2173749)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (1825741..1830943)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 23 Neighboring gene desmoplakin a Neighboring gene uncharacterized LOC137487662 Neighboring gene coiled-coil domain containing 13 Neighboring gene transmembrane inner ear

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mitochondrial respirasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    HIG1 domain family member 1A, mitochondrial
    Names
    hypoxia induced gene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200100.2NP_956394.1  HIG1 domain family member 1A, mitochondrial

      See identical proteins and their annotated locations for NP_956394.1

      Status: VALIDATED

      Source sequence(s)
      CU929426, EH437255, EH459895
      UniProtKB/TrEMBL
      Q6P5L9, Q7ZZZ4
      Related
      ENSDARP00000033361.7, ENSDART00000029347.8
      Conserved Domains (1) summary
      pfam04588
      Location:2169
      HIG_1_N; Hypoxia induced protein conserved region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      2168547..2173749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)