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    lgals4 galectin 4 [ Danio rerio (zebrafish) ]

    Gene ID: 567193, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lgals4provided by ZNC
    Official Full Name
    galectin 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-141222-13
    See related
    Ensembl:ENSDARG00000104016 AllianceGenome:ZFIN:ZDB-GENE-141222-13
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-151j17.4
    Summary
    Predicted to enable carbohydrate binding activity. Orthologous to human LGALS4 (galectin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lgals4 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    60
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (50650641..50672461)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (50654082..50675898)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2Q family member 1 Neighboring gene cholinergic receptor, nicotinic, beta 4 (neuronal) Neighboring gene cholinergic receptor, nicotinic, alpha 3 Neighboring gene purinergic receptor P2Y1 Neighboring gene RAP2B, member of RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach. Banu S, et al. Genomics, 2022 Mar. PMID 35134499
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein lgals4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      50650641..50672461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173698.5 → XP_005173755.1  uncharacterized protein lgals4 isoform X1

      UniProtKB/TrEMBL
      A0A0R4II06, A0A8M2BKY6, A0A8M2BLB8, A0A8M3AJV8, A0A8M6YW93
      Related
      ENSDARP00000134965.2, ENSDART00000161022.3
      Conserved Domains (2) summary
      cd00070
      Location:216 → 340
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
      pfam00337
      Location:1152 → 1279
      Gal-bind_lectin; Galactoside-binding lectin

    2. XM_005173700.5 → XP_005173757.1  uncharacterized protein lgals4 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BKZ8, A0A8M3AJV8
      Conserved Domains (2) summary
      cd00070
      Location:216 → 340
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
      pfam00337
      Location:1152 → 1279
      Gal-bind_lectin; Galactoside-binding lectin

    3. XM_068214976.1 → XP_068071077.1  uncharacterized protein lgals4 isoform X3

      UniProtKB/TrEMBL
      A0A8M2BL00

    4. XM_005173704.5 → XP_005173761.1  uncharacterized protein lgals4 isoform X4

      See identical proteins and their annotated locations for XP_005173761.1

      UniProtKB/TrEMBL
      A0A8M2BKZ5, A0A8M2BL00
      Conserved Domains (2) summary
      cd00070
      Location:216 → 340
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
      pfam00337
      Location:528 → 655
      Gal-bind_lectin; Galactoside-binding lectin
    Nucleotide Protein Strain
    Heading Accession and Version

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