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    rmi1 RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

    Gene ID: 393149, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rmi1provided by ZNC
    Official Full Name
    RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-829
    See related
    Ensembl:ENSDARG00000041376 AllianceGenome:ZFIN:ZDB-GENE-040426-829
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55882
    Summary
    Predicted to enable nucleotide binding activity. Predicted to be involved in double-strand break repair via homologous recombination and resolution of meiotic recombination intermediates. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleus. Predicted to be part of RecQ family helicase-topoisomerase III complex. Predicted to be active in nuclear body. Orthologous to human RMI1 (RecQ mediated genome instability 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rmi1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (49766391..49769988)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (49777622..49781219)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene Q-nucleotide N-glycosylase 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K Neighboring gene neurotrophic tyrosine kinase, receptor, type 2a Neighboring gene ATP/GTP binding carboxypeptidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A Genetic Model to Study Increased Hexosamine Biosynthetic Flux. Hugo SE, et al. Endocrinology, 2017 Aug 1. PMID 28582574, Free PMC Article
    2. Evolution after Whole-Genome Duplication: Teleost MicroRNAs. Desvignes T, et al. Mol Biol Evol, 2021 Jul 29. PMID 33871629, Free PMC Article
    3. Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. Li L, et al. FASEB J, 2022 Nov. PMID 36208295
    4. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. Tiefenbach J, et al. PLoS One, 2010 Mar 22. PMID 20339547, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC55882

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in resolution of meiotic recombination intermediates IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RecQ family helicase-topoisomerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    recQ-mediated genome instability protein 1
    Names
    RecQ mediated genome instability 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200180.1 → NP_956474.1  recQ-mediated genome instability protein 1

      See identical proteins and their annotated locations for NP_956474.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045482
      UniProtKB/Swiss-Prot
      Q7ZVM9
      UniProtKB/TrEMBL
      B2GPA1
      Related
      ENSDARP00000060656.3, ENSDART00000060657.4
      Conserved Domains (2) summary
      pfam08585
      Location:14 → 198
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:382 → 510
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      49766391..49769988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021478211.2 → XP_021333886.1  recQ-mediated genome instability protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QDM9
      Related
      ENSDARP00000148311.1, ENSDART00000184764.1
      Conserved Domains (2) summary
      pfam08585
      Location:13 → 204
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:382 → 510
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7ZVM9.1 GenPept UniProtKB/Swiss-Prot:Q7ZVM9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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