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    erlin2 ER lipid raft associated 2 [ Danio rerio (zebrafish) ]

    Gene ID: 100151163, updated on 9-Dec-2024

    Summary

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    Official Symbol
    erlin2provided by ZNC
    Official Full Name
    ER lipid raft associated 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090505-4
    See related
    Ensembl:ENSDARG00000086523 AllianceGenome:ZFIN:ZDB-GENE-090505-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See erlin2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (35463737..35487953)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (34863584..34887800)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 33 Neighboring gene fructose-1,6-bisphosphatase 1b Neighboring gene cholesterol 25-hydroxylase like 3 Neighboring gene si:dkey-204l11.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. Pereiro P, et al. Antiviral Res, 2017 Sep. PMID 28789986
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    erlin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128415.1 → NP_001121887.1  erlin-2

      See identical proteins and their annotated locations for NP_001121887.1

      Status: PROVISIONAL

      Source sequence(s)
      CR762390
      UniProtKB/Swiss-Prot
      A3QK16
      Related
      ENSDARP00000121177.1, ENSDART00000131286.2
      Conserved Domains (3) summary
      smart00244
      Location:20 → 186
      PHB; prohibitin homologues
      cd03406
      Location:19 → 306
      SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
      TIGR02794
      Location:186 → 274
      tolA_full; TolA protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      35463737..35487953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394591.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      293781..317997
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A3QK16.1 GenPept UniProtKB/Swiss-Prot:A3QK16

    Gene LinkOut

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