tbl2 transducin beta like 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tbl2provided by ZNC
Official Full Name: transducin beta like 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9012
See related: Ensembl:ENSDARG00000043357 AllianceGenome:ZFIN:ZDB-GENE-030131-9012
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa96f08
Summary: Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be active in endoplasmic reticulum. Is expressed in yolk syncytial layer. Orthologous to human TBL2 (transducin beta like 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (33254715..33265688, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (33310854..33321817, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum unfolded protein response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: transducin beta-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212767.1 → NP_997932.1 transducin beta-like protein 2

See identical proteins and their annotated locations for NP_997932.1

Status: PROVISIONAL

Source sequence(s)

BC065682

UniProtKB/TrEMBL

Q6P0B5

Related

ENSDARP00000063641.4, ENSDART00000063642.6

Conserved Domains (3) summary

COG2319
Location:78 → 411

WD40; WD40 repeat [General function prediction only]

sd00039
Location:87 → 130

7WD40; WD40 repeat [structural motif]

cl02567
Location:76 → 390

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007121.7 Reference GRCz11 Primary Assembly

Range

33254715..33265688 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005172641.5 → XP_005172698.1 transducin beta-like protein 2 isoform X1

UniProtKB/TrEMBL

A0A8M2BJZ4, E7F4J8

Conserved Domains (3) summary

COG2319
Location:78 → 411

WD40; WD40 repeat [General function prediction only]

sd00039
Location:87 → 130

7WD40; WD40 repeat [structural motif]

cl02567
Location:76 → 390

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...