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    zgc:101772 zgc:101772 [ Danio rerio (zebrafish) ]

    Gene ID: 447886, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zgc:101772provided by ZNC
    Official Full Name
    zgc:101772provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-51
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040912-51
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be active in membrane. Is expressed in several structures, including cranial ganglion; hatching gland; mucus secreting cell; olfactory system; and pronephric duct. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human MAL (mal, T cell differentiation protein). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: only annotated on alternate loci in reference assembly
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    Genomic context

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    See zgc:101772 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 Unlocalized Scaffold (ALT_DRER_TU_1) NW_018394986.1 (361058..364992)

    NW_018394986.1Genomic Context describing neighboring genes Neighboring gene mitoregulin Neighboring gene nephronophthisis 1 Neighboring gene mitochondrial ribosomal protein S5 Neighboring gene uncharacterized LOC103908810

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_018394986.1 Chromosome 17 Reference GRCz11 ALT_DRER_TU_1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. Krens SF, et al. BMC Genomics, 2008 Apr 28. PMID 18442396, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of myelin sheath IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in myelination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC447886
    Names
    T-lymphocyte maturation-associated protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004625.1 → NP_001004625.1  uncharacterized protein LOC447886

      See identical proteins and their annotated locations for NP_001004625.1

      Status: PREDICTED

      Source sequence(s)
      BC081401
      UniProtKB/TrEMBL
      Q66ID0
      Conserved Domains (1) summary
      pfam01284
      Location:18 → 151
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394986.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      361058..364992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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