dcun1d2b DCN1, defective in cullin neddylation 1, domain containing 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dcun1d2bprovided by ZNC
Official Full Name: DCN1, defective in cullin neddylation 1, domain containing 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-171
See related: Ensembl:ENSDARG00000041592 AllianceGenome:ZFIN:ZDB-GENE-040625-171
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dcun1d2; fj80d04; zgc:86658; wu:fj80d04
Summary: Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in protein neddylation. Predicted to be part of ubiquitin ligase complex. Orthologous to human DCUN1D2 (defective in cullin neddylation 1 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (208177..214917, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (212998..219732, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cullin family protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin conjugating enzyme binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-like protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein neddylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DCN1-like protein 2b

Names: DCN1, defective in cullin neddylation 1, domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002156.2 → NP_001002156.2 DCN1-like protein 2b

Status: VALIDATED

Source sequence(s)

CU929326

UniProtKB/TrEMBL

A0A8M9P764, Q6IQR0

Related

ENSDARP00000060970.4, ENSDART00000060971.5

Conserved Domains (1) summary

pfam03556
Location:81 → 191

Cullin_binding; Cullin binding