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    Vmn2r42 vomeronasal 2, receptor 42 [ Mus musculus (house mouse) ]

    Gene ID: 22310, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vmn2r42provided by MGI
    Official Full Name
    vomeronasal 2, receptor 42provided by MGI
    Primary source
    MGI:MGI:1316666
    See related
    Ensembl:ENSMUSG00000070844 AllianceGenome:MGI:1316666
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    V2r4
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r42 in Genome Data Viewer
    Location:
    7 A1; 7 5.8 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (8186264..8203319, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (8183265..8200320, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 31 pseudogene Neighboring gene vomeronasal 2, receptor 41 Neighboring gene vomeronasal 2, receptor 43 Neighboring gene predicted gene 3654

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
    2. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transposon induced (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor 42
    Names
    vomeronasal 2, receptor, 4
    vomeronasal organ family 2, receptor, 4
    vomeronasal receptor Vmn2r42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009493.2 → NP_033519.1  vomeronasal 2, receptor 42 precursor

      See identical proteins and their annotated locations for NP_033519.1

      Status: VALIDATED

      Source sequence(s)
      AF011414
      Consensus CDS
      CCDS57483.1
      UniProtKB/TrEMBL
      O35192, O35202
      Related
      ENSMUSP00000083463.6, ENSMUST00000086282.13
      Conserved Domains (4) summary
      pfam00003
      Location:599 → 833
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:75 → 453
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:513 → 564
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:43 → 503
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      8186264..8203319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322129.1 → XP_017177618.1  vomeronasal 2, receptor 42 isoform X1

      UniProtKB/TrEMBL
      D3Z1K8, O35202
      Related
      ENSMUSP00000119761.2, ENSMUST00000146278.9
      Conserved Domains (3) summary
      cd15283
      Location:551 → 786
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:512 → 556
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:43 → 503
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    2. XM_036152917.1 → XP_036008810.1  vomeronasal 2, receptor 42 isoform X2

      UniProtKB/TrEMBL
      D3YZ97
      Related
      ENSMUSP00000123451.2, ENSMUST00000142934.3
      Conserved Domains (2) summary
      pfam07562
      Location:512 → 553
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:43 → 503
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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