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    Ptrhd1 peptidyl-tRNA hydrolase domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 69709, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptrhd1provided by MGI
    Official Full Name
    peptidyl-tRNA hydrolase domain containing 1provided by MGI
    Primary source
    MGI:MGI:1916959
    See related
    Ensembl:ENSMUSG00000096199 AllianceGenome:MGI:1916959
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410017P09Rik
    Summary
    Predicted to enable aminoacyl-tRNA hydrolase activity. Orthologous to human PTRHD1 (peptidyl-tRNA hydrolase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 12.6), adrenal adult (RPKM 5.7) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ptrhd1 in Genome Data Viewer
    Location:
    12 A1.1; 12 2.04 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (4284013..4290123)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (4234013..4240123)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_31436 Neighboring gene adenylate cyclase 3 Neighboring gene predicted gene, 53749 Neighboring gene centromere protein O Neighboring gene ubiquitin associated protein 2-like pseudogene Neighboring gene predicted gene, 29696 Neighboring gene nuclear receptor coactivator 1 Neighboring gene STARR-seq mESC enhancer starr_31441 Neighboring gene STARR-seq mESC enhancer starr_31442 Neighboring gene aurora kinase A pseudogene Neighboring gene STARR-seq mESC enhancer starr_31447 Neighboring gene predicted gene, 51963

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General protein information

    Preferred Names
    putative peptidyl-tRNA hydrolase PTRHD1
    Names
    peptidyl-tRNA hydrolase domain-containing protein 1
    NP_001191841.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204912.2NP_001191841.1  putative peptidyl-tRNA hydrolase PTRHD1

      See identical proteins and their annotated locations for NP_001191841.1

      Status: VALIDATED

      Source sequence(s)
      AC162932
      Consensus CDS
      CCDS56829.1
      UniProtKB/Swiss-Prot
      D3Z4S3
      Related
      ENSMUSP00000137070.2, ENSMUST00000179139.3
      Conserved Domains (1) summary
      cl19212
      Location:25139
      PTH2_family; Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      4284013..4290123
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)