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    UGT73B2 UDP-glucosyltransferase 73B2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829560, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGT73B2
    Official Full Name
    UDP-glucosyltransferase 73B2
    Primary source
    TAIR:AT4G34135
    Locus tag
    AT4G34135
    See related
    Araport:AT4G34135
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    UDP-glucosyltransferase 73B2
    Summary
    The At4g34135 gene encodes a flavonol 7-O-glucosyltransferase (EC 2.4.1.237) that glucosylates also with a 20 fold lower activity flavonols (kaempferol and quercetin) at the 3-O-position.
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    Genomic context

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    See UGT73B2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (16345150..16347434, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Cystathionine beta-synthase (CBS) family protein Neighboring gene ncRNA Neighboring gene UDP-glucosyl transferase 73B3 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene UDP-glucosyl transferase 73B1 Neighboring gene D111/G-patch domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bio-fermentation of modified flavonoids: an example of in vivo diversification of secondary metabolites. Willits MG, et al. Phytochemistry, 2004 Jan. PMID 14697269
    2. Pathogen-responsive expression of glycosyltransferase genes UGT73B3 and UGT73B5 is necessary for resistance to Pseudomonas syringae pv tomato in Arabidopsis. Langlois-Meurinne M, et al. Plant Physiol, 2005 Dec. PMID 16306146, Free PMC Article
    3. Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases. Gandia-Herrero F, et al. Plant J, 2008 Dec. PMID 18702669
    4. Arabidopsis glycosyltransferases as biocatalysts in fermentation for regioselective synthesis of diverse quercetin glucosides. Lim EK, et al. Biotechnol Bioeng, 2004 Sep 5. PMID 15352060
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_119575.2
    NM_179161.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavonol 3-O-glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables flavonol 7-O-beta-glucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables quercetin 7-O-glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within flavonol biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to other organism IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucosyltransferase 73B2
    NP_567954.1
    • UDP-glucosyltransferase 73B2 (UGT73B2); FUNCTIONS IN: flavonol 3-O-glucosyltransferase activity, UDP-glycosyltransferase activity, quercetin 7-O-glucosyltransferase activity, UDP-glucosyltransferase activity; INVOLVED IN: flavonol biosynthetic process, response to other organism; LOCATED IN: endomembrane system; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-glucosyl transferase 73B3 (TAIR:AT4G34131.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_849492.1
    • UDP-glucosyltransferase 73B2 (UGT73B2); FUNCTIONS IN: flavonol 3-O-glucosyltransferase activity, UDP-glycosyltransferase activity, quercetin 7-O-glucosyltransferase activity, UDP-glucosyltransferase activity; INVOLVED IN: flavonol biosynthetic process, response to other organism; LOCATED IN: endomembrane system; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-glucosyl transferase 73B3 (TAIR:AT4G34131.1); Has 4778 Blast hits to 4740 proteins in 170 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 4776; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16345150..16347434 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119575.2 → NP_567954.1  UDP-glucosyltransferase 73B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567954.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94C57
      UniProtKB/TrEMBL
      A0A5S9XZC2, A0A654FVF8, W8QND5
      Conserved Domains (2) summary
      PLN03007
      Location:5 → 483
      PLN03007; UDP-glucosyltransferase family protein
      TIGR01426
      Location:15 → 441
      MGT; glycosyltransferase, MGT family

    2. NM_179161.2 → NP_849492.1  UDP-glucosyltransferase 73B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849492.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JKK6, Q8L9I7
      Conserved Domains (1) summary
      cl10013
      Location:5 → 331
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94C57.1

    Gene LinkOut

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