ASN2 asparagine synthetase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ASN2
Official Full Name: asparagine synthetase 2
Primary source: TAIR:AT5G65010
Locus tag: AT5G65010
See related: Araport:AT5G65010
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: asparagine synthetase 2; ASPARAGINE SYNTHETASE 2; MXK3.25; MXK3_25
Summary: Encodes asparagine synthetase (ASN2).
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

ASN2 is essential for nitrogen assimilation, distribution and remobilization (via the phloem) within the plant.
Title: Arabidopsis thaliana ASN2 encoding asparagine synthetase is involved in the control of nitrogen assimilation and export during vegetative growth.
The results indicate that the asn2-1 knockout mutant was impaired in nitrogen assimilation and translocation under salt treatment.
Title: An Arabidopsis mutant disrupted in ASN2 encoding asparagine synthetase 2 exhibits low salt stress tolerance.

Submit: New GeneRIF Correction

NM_125900.2

NM_180941.3

Function	Evidence Code	Pubs
enables asparagine synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info
enables aspartate-ammonia ligase activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in L-asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ammonium ion metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within asparagine biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within hyperosmotic salinity response	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in plasmodesma	HDA more info	PubMed

NP_201306.2

asparagine synthetase 2 (ASN2); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 3 (TAIR:AT5G10240.1); Has 12646 Blast hits to 12280 proteins in 2301 species: Archae - 400; Bacteria - 7857; Metazoa - 213; Fungi - 272; Plants - 420; Viruses - 7; Other Eukaryotes - 3477 (source: NCBI BLink).

NP_851272.1

asparagine synthetase 2 (ASN2); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 3 (TAIR:AT5G10240.1); Has 12695 Blast hits to 12327 proteins in 2309 species: Archae - 403; Bacteria - 7898; Metazoa - 213; Fungi - 273; Plants - 424; Viruses - 7; Other Eukaryotes - 3477 (source: NCBI BLink).