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    WRKY21 WRKY DNA-binding protein 21 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817609, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WRKY21
    Official Full Name
    WRKY DNA-binding protein 21
    Primary source
    TAIR:AT2G30590
    Locus tag
    AT2G30590
    See related
    Araport:AT2G30590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6B20.6; T6B20_6; WRKY DNA-binding protein 21
    Summary
    Encodes WRKY DNA-binding protein 21 (WRKY21).
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    Genomic context

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    See WRKY21 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (13033418..13035797)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene los glycosyltransferase 5 Neighboring gene DREB2A-interacting protein 2 Neighboring gene BTB/POZ domain-containing protein Neighboring gene F-box/LRR protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. WRKY group IId transcription factors interact with calmodulin. Park CY, et al. FEBS Lett, 2005 Feb 28. PMID 15733871
    2. The WRKY superfamily of plant transcription factors. Eulgem T, et al. Trends Plant Sci, 2000 May. PMID 10785665
    3. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Sparks EE, et al. Dev Cell, 2016 Dec 5. PMID 27923776, Free PMC Article
    4. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article
    5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128611.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables calmodulin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucosinolate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WRKY DNA-binding protein 21
    NP_565703.1
    • WRKY DNA-binding protein 21 (WRKY21); FUNCTIONS IN: calmodulin binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657), Transcription factor, WRKY, Zn-cluster (InterPro:IPR018872); BEST Arabidopsis thaliana protein match is: WRKY DNA-binding protein 74 (TAIR:AT5G28650.1); Has 39192 Blast hits to 15053 proteins in 688 species: Archae - 6; Bacteria - 1092; Metazoa - 13773; Fungi - 4123; Plants - 4597; Viruses - 447; Other Eukaryotes - 15154 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13033418..13035797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128611.3 → NP_565703.1  WRKY DNA-binding protein 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565703.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04336
      UniProtKB/TrEMBL
      A0A178VWW8, A0A5S9X2P6
      Conserved Domains (3) summary
      smart00774
      Location:313 → 370
      WRKY; DNA binding domain
      pfam10533
      Location:273 → 310
      Plant_zn_clust; Plant zinc cluster domain
      cl11978
      Location:5 → 102
      DUF2333; Uncharacterized protein conserved in bacteria (DUF2333)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04336.1

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