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    HCC1 electron transport SCO1/SenC family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820046, updated on 18-Sep-2024

    Summary

    Official Symbol
    HCC1
    Official Full Name
    electron transport SCO1/SenC family protein
    Primary source
    TAIR:AT3G08950
    Locus tag
    AT3G08950
    See related
    Araport:AT3G08950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    homologue of the copper chaperone SCO1
    Summary
    Encodes HCC1, homologue of the copper chaperone SCO1 (synthesis of cytochrome c oxidase 1) from the yeast Saccharomyces cerevisiae. SCO1 encodes a mitochondrial protein that is essential for the correct assembly of complex IV in the respiratory chain. HCC1 is localized in the mitochondrion. A chimeric yeast Sco1-Arabidopsis HCC1 protein complements yeast Sco1 activity. Embryos of hcc1 mutants became arrested at various developmental stages, mostly at the heart stage.
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    Genomic context

    See HCC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (2727193..2729656)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene light harvesting complex photosystem II Neighboring gene ARM repeat superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene Peptidase S24/S26A/S26B/S26C family protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_111729.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in mitochondrion PubMed 
    located_in mitochondrion PubMed 
    located_in mitochondrion  

    General protein information

    Preferred Names
    electron transport SCO1/SenC family protein
    NP_566339.1
    • electron transport SCO1/SenC family protein; FUNCTIONS IN: copper ion binding; INVOLVED IN: copper ion transport, respiratory chain complex IV assembly, cellular copper ion homeostasis, cell redox homeostasis; LOCATED IN: mitochondrion, mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Synthesis of cytochrome c oxidase, Sco1/Sco2 (InterPro:IPR017276), Copper chaperone SCO1/SenC (InterPro:IPR003782), Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT4G39740.1); Has 4072 Blast hits to 4072 proteins in 1098 species: Archae - 11; Bacteria - 2439; Metazoa - 165; Fungi - 147; Plants - 84; Viruses - 0; Other Eukaryotes - 1226 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2727193..2729656
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111729.3 → NP_566339.1  electron transport SCO1/SenC family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566339.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VYP0, Q9SR94
      UniProtKB/TrEMBL
      A0A178VMU8, A0A5S9XAL6
      Conserved Domains (1) summary
      cd02968
      Location:173 → 313
      SCO; SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c ...
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