U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RAD23D Rad23 UV excision repair protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833835, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RAD23D
    Official Full Name
    Rad23 UV excision repair protein family
    Primary source
    TAIR:AT5G38470
    Locus tag
    AT5G38470
    See related
    Araport:AT5G38470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MXI10.20; MXI10_20; RADIATION SENSITIVE23D
    Summary
    Encodes a member of the RADIATION SENSITIVE23 (RAD23) family: AT1G16190(RAD23A), AT1G79650(RAD23B), AT3G02540(RAD23C), AT5G38470(RAD23D). RAD23 proteins play an essential role in the cell cycle, morphology, and fertility of plants through their delivery of UPS (ubiquitin/26S proteasome system) substrates to the 26S proteasome.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RAD23D in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (15404622..15407745)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 735, subfamily A, polypeptide 1 Neighboring gene ALG6, ALG8 glycosyltransferase family Neighboring gene ncRNA Neighboring gene general regulatory factor 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The RAD23 family provides an essential connection between the 26S proteasome and ubiquitylated proteins in Arabidopsis. Farmer LM, et al. Plant Cell, 2010 Jan. PMID 20086187, Free PMC Article
    2. Mass spectrometric approach for identifying putative plasma membrane proteins of Arabidopsis leaves associated with cold acclimation. Kawamura Y, et al. Plant J, 2003 Oct. PMID 14535880
    3. Telomerase Interaction Partners-Insight from Plants. Fulnečková J, et al. Int J Mol Sci, 2021 Dec 29. PMID 35008793, Free PMC Article
    4. Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. Majerská J, et al. Protoplasma, 2017 Jul. PMID 27853871
    5. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001085211.1
    NM_123208.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables proteasome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Rad23 UV excision repair protein family
    NP_001078680.1
    • RADIATION SENSITIVE23D (RAD23D); FUNCTIONS IN: damaged DNA binding, ubiquitin binding, proteasome binding; INVOLVED IN: response to cold, nucleotide-excision repair; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock chaperonin-binding (InterPro:IPR006636), Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), UV excision repair protein Rad23 (InterPro:IPR004806), Ubiquitin (InterPro:IPR000626), XPC-binding domain (InterPro:IPR015360), Ubiquitin supergroup (InterPro:IPR019955), UBA-like (InterPro:IPR009060); BEST Arabidopsis thaliana protein match is: Rad23 UV excision repair protein family (TAIR:AT3G02540.3); Has 11236 Blast hits to 6362 proteins in 878 species: Archae - 4; Bacteria - 655; Metazoa - 4543; Fungi - 1476; Plants - 2522; Viruses - 172; Other Eukaryotes - 1864 (source: NCBI BLink).
    NP_198663.1
    • RADIATION SENSITIVE23D (RAD23D); FUNCTIONS IN: damaged DNA binding, ubiquitin binding, proteasome binding; INVOLVED IN: response to cold, nucleotide-excision repair; LOCATED IN: nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock chaperonin-binding (InterPro:IPR006636), Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), UV excision repair protein Rad23 (InterPro:IPR004806), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), Ubiquitin (InterPro:IPR000626), XPC-binding domain (InterPro:IPR015360), Ubiquitin supergroup (InterPro:IPR019955), UBA-like (InterPro:IPR009060); BEST Arabidopsis thaliana protein match is: Rad23 UV excision repair protein family (TAIR:AT3G02540.3); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15404622..15407745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123208.2 → NP_198663.1  Rad23 UV excision repair protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198663.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84L30, Q94C35, Q9FF16
      UniProtKB/TrEMBL
      A0A178UR87, A0A5S9Y9M4
      Conserved Domains (1) summary
      TIGR00601
      Location:1 → 374
      rad23; UV excision repair protein Rad23

    2. NM_001085211.1 → NP_001078680.1  Rad23 UV excision repair protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078680.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UR87, A8MR76
      Conserved Domains (4) summary
      cd01805
      Location:1 → 77
      RAD23_N; Ubiquitin-like domain of RAD23
      smart00213
      Location:1 → 74
      UBQ; Ubiquitin homologues
      cd14379
      Location:142 → 191
      UBA1_Rad23_plant; UBA1 domain of putative DNA repair proteins Rad23 found in plant
      pfam09280
      Location:253 → 308
      XPC-binding; XPC-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84L30.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools