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    MKK8 MAP kinase kinase 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819797, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MKK8
    Official Full Name
    MAP kinase kinase 8
    Primary source
    TAIR:AT3G06230
    Locus tag
    AT3G06230
    See related
    Araport:AT3G06230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMKK8; F28L1.17; F28L1_17; MAP kinase kinase 8
    Summary
    member of MAP Kinase Kinase
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    Genomic context

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    See MKK8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (1885496..1886377)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene F-box family protein Neighboring gene FAR1-related sequence 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MAP kinase signalling cascade in Arabidopsis innate immunity. Asai T, et al. Nature, 2002 Feb 28. PMID 11875555
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables MAP kinase kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within MAPK cascade TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    MAP kinase kinase 8
    NP_187274.1
    • MAP kinase kinase 8 (MKK8); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: protein amino acid phosphorylation; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAP kinase kinase 9 (TAIR:AT1G73500.1); Has 118422 Blast hits to 117448 proteins in 4367 species: Archae - 104; Bacteria - 13467; Metazoa - 44308; Fungi - 11331; Plants - 29630; Viruses - 467; Other Eukaryotes - 19115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1885496..1886377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111498.1 → NP_187274.1  MAP kinase kinase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187274.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M8J5
      UniProtKB/TrEMBL
      A0A178VCP5
      Conserved Domains (2) summary
      smart00220
      Location:56 → 293
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:51 → 293
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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