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    GRF5 general regulatory factor 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831462, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GRF5
    Official Full Name
    general regulatory factor 5
    Primary source
    TAIR:AT5G16050
    Locus tag
    AT5G16050
    See related
    Araport:AT5G16050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1N13.190; F1N13_190; general regulatory factor 5; GF14 UPSILON; GF14 UPSILON CHAIN
    Summary
    Encodes GF14 upsilon chain, a 14-3-3 gene family member.
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    Genomic context

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    See GRF5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (5243555..5245838, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene mental retardation GTPase activating protein Neighboring gene ncRNA Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene Cytochrome c oxidase biogenesis protein Cmc1-like protein Neighboring gene TCP-1/cpn60 chaperonin family protein Neighboring gene carboxyesterase 17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GROWTH REGULATING FACTOR5 stimulates Arabidopsis chloroplast division, photosynthesis, and leaf longevity. Vercruyssen L, et al. Plant Physiol, 2015 Mar. PMID 25604530, Free PMC Article
    2. The Arabidopsis 14-3-3 multigene family. Wu K, et al. Plant Physiol, 1997 Aug. PMID 9276953, Free PMC Article
    3. Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1. Pignocchi C, et al. Ann Bot, 2011 May. PMID 21558460, Free PMC Article
    4. Light modulated activity of root alkaline/neutral invertase involves the interaction with 14-3-3 proteins. Gao J, et al. Plant J, 2014 Dec. PMID 25256212
    5. Plasma Membrane CRPK1-Mediated Phosphorylation of 14-3-3 Proteins Induces Their Nuclear Import to Fine-Tune CBF Signaling during Cold Response. Liu Z, et al. Mol Cell, 2017 Apr 6. PMID 28344081

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GRF5 stimulates chloroplast division, resulting in a higher chloroplast number per cell with a concomitant increase in chlorophyll levels.
      Title: GROWTH REGULATING FACTOR5 stimulates Arabidopsis chloroplast division, photosynthesis, and leaf longevity.
    2. 14-3-3 upsilon most strongly associates with EDE1 in its free form, but also weakly when EDE1 is bound to microtubules. [14-3-3 upsilon]
      Title: Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001343435.1
    NM_121610.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphorylated amino acid binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    general regulatory factor 5
    NP_568325.1
    • general regulatory factor 5 (GRF5); FUNCTIONS IN: protein phosphorylated amino acid binding, ATP binding; INVOLVED IN: response to cadmium ion; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: 14-3-3 protein (InterPro:IPR000308); BEST Arabidopsis thaliana protein match is: general regulatory factor 7 (TAIR:AT3G02520.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5243555..5245838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121610.4 → NP_568325.1  general regulatory factor 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568325.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42645
      UniProtKB/TrEMBL
      A0A178UKR5, A0A5S9Y4J2
      Conserved Domains (1) summary
      smart00101
      Location:7 → 250
      14_3_3; 14-3-3 homologues

    2. NM_001343435.1 → NP_001331015.1  general regulatory factor 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42645
      UniProtKB/TrEMBL
      A0A178UKR5, A0A5S9Y4J2
      Conserved Domains (1) summary
      smart00101
      Location:7 → 250
      14_3_3; 14-3-3 homologues
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42645.2

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