SUP C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SUP
Official Full Name: C2H2 and C2HC zinc fingers superfamily protein
Primary source: TAIR:AT3G23130
Locus tag: AT3G23130
See related: Araport:AT3G23130
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: FLO10; FLORAL DEFECTIVE 10; FLORAL ORGAN NUMBER 1; FON1; SUPERMAN
Summary: Flower-specific gene controlling the boundary of the stamen and carpel whorls. Similar to zinc finger transcription factors.
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Genomic context

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See SUP in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 1

Sequence:: Chromosome: 3; NC_003074.8 (8242256..8243372)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SUPERMAN genes: uncovering a new function in the development of complex inflorescences.
Title: SUPERMAN genes: uncovering a new function in the development of complex inflorescences.
My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
Title: My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
Our work presents a new floral meristem regulatory mechanism, in which SUP, a boundary gene, coordinates floral organogenesis and floral meristem size through fine-tuning auxin biosynthesis.
Title: SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis.
SUPERMAN gene is required for proper specification of the boundary between stamens in whorl 3 and carpels in whorl 4, as superman mutants exhibit supernumerary stamens but usually lack carpels; the extra stamens in superman mutants arise from cells in whorl 4, which change their fate from female to male, while floral stem cells proliferate longer, allowing for the production of additional stamens
Title: SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers.
Sup role in resolving male/female gradients into sharp male and female identities (whorls, organs) and in enforcing flower homeostasis during evolution
Title: Analysis of the Arabidopsis superman allelic series and the interactions with other genes demonstrate developmental robustness and joint specification of male-female boundary, flower meristem termination and carpel compartmentalization.
Arabidopsis superman regulate hormone signalling and mediate cell proliferation and differentiation.
Title: Arabidopsis and Tobacco superman regulate hormone signalling and mediate cell proliferation and differentiation.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MASC_STS16072 (e-PCR)
- UniSTS:258846

Homology

Orthologs from OrthoDB

NM_113214.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	TAS Traceable Author Statement more info	PubMed
enables DNA-binding transcription factor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within flower development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within formation of plant organ boundary	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within hormone-mediated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within negative regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of cell size	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within specification of floral organ identity	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within specification of floral organ identity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in specification of floral organ identity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: C2H2 and C2HC zinc fingers superfamily protein

NP_188954.1

SUPERMAN (SUP); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding, nucleic acid binding; INVOLVED IN: flower development, negative regulation of transcription, specification of floral organ identity; LOCATED IN: intracellular; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: zinc finger protein 11 (TAIR:AT2G42410.1); Has 1049 Blast hits to 1049 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 37; Fungi - 0; Plants - 1011; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

8242256..8243372

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_113214.2 → NP_188954.1 C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188954.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q38895, Q4PSN1

UniProtKB/TrEMBL

A0A178VCV9, A0A654FA20, C0SVC6

Conserved Domains (1) summary

pfam13912
Location:47 → 71

zf-C2H2_6; C2H2-type zinc finger