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    TCP15 TCP family transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843305, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TCP15
    Official Full Name
    TCP family transcription factor
    Primary source
    TAIR:AT1G69690
    Locus tag
    AT1G69690
    See related
    Araport:AT1G69690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTCP15; T6C23.11; T6C23_11; TEOSINTE BRANCHED1/CYCLOIDEA/PCF 15
    Summary
    AtTCP15 is involved in the regulation of endoreduplication.
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    Genomic context

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    See TCP15 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (26216009..26218071)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene HVA22 homologue C Neighboring gene Regulator of chromosome condensation (RCC1) family with FYVE zinc finger domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis transcription factor AtTCP15 regulates endoreduplication by modulating expression of key cell-cycle genes. Li ZY, et al. Mol Plant, 2012 Jan. PMID 21992944
    2. Redox modulation of plant developmental regulators from the class I TCP transcription factor family. Viola IL, et al. Plant Physiol, 2013 Jul. PMID 23686421, Free PMC Article
    3. TCP15 modulates cytokinin and auxin responses during gynoecium development in Arabidopsis. Lucero LE, et al. Plant J, 2015 Oct. PMID 26303297
    4. The class I protein AtTCP15 modulates plant development through a pathway that overlaps with the one affected by CIN-like TCP proteins. Uberti-Manassero NG, et al. J Exp Bot, 2012 Jan. PMID 22016421
    5. Class-I TCP Transcription Factors Activate the SAUR63 Gene Subfamily in Gibberellin-Dependent Stamen Filament Elongation. Gastaldi V, et al. Plant Physiol, 2020 Apr. PMID 31988200, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Class I TCP transcription factors TCP14 and TCP15 promote axillary branching in Arabidopsis by counteracting the action of Class II TCP BRANCHED1.
      Title: Class I TCP transcription factors TCP14 and TCP15 promote axillary branching in Arabidopsis by counteracting the action of Class II TCP BRANCHED1.
    2. The trxG protein ULT1 regulates Arabidopsis organ size by interacting with TCP14/15 to antagonize the LIM peptidase DA1 for H3K4me3 on target genes.
      Title: The trxG protein ULT1 regulates Arabidopsis organ size by interacting with TCP14/15 to antagonize the LIM peptidase DA1 for H3K4me3 on target genes.
    3. DNA-TCP complex structures reveal a unique recognition mechanism for TCP transcription factor families.
      Title: DNA-TCP complex structures reveal a unique recognition mechanism for TCP transcription factor families.
    4. Arabidopsis thaliana TCP15 interacts with the MIXTA-like transcription factor MYB106/NOECK.
      Title: Arabidopsis thaliana TCP15 interacts with the MIXTA-like transcription factor MYB106/NOECK.
    5. Class I TCP proteins TCP14 and TCP15 are required for elongation and gene expression responses to auxin.
      Title: Class I TCP proteins TCP14 and TCP15 are required for elongation and gene expression responses to auxin.
    6. This study investigated and revealed a role for MOS1 in transcriptional regulation through TCP15 and its homologues. This finding suggests the coordination of cell-cycle progression and plant immune responses at multiple levels.
      Title: MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    7. posttranslational modification of TCP14/15 by SPY inhibits their proteolysis.
      Title: The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    8. TCP15 acts as a repressor of anthocyanin accumulation acting on the expression of anthocyanin biosynthesis genes and upstream transcriptional regulators.
      Title: Redox-Dependent Modulation of Anthocyanin Biosynthesis by the TCP Transcription Factor TCP15 during Exposure to High Light Intensity Conditions in Arabidopsis.
    9. DA1, DAR1, and DAR2 physically interact with the transcription factors TCP14 and TCP15, which repress endoreduplication.
      Title: The ubiquitin receptors DA1, DAR1, and DAR2 redundantly regulate endoreduplication by modulating the stability of TCP14/15 in Arabidopsis.
    10. TCP14 and TCP15 act downstream of the gibberellins and promote seed germination.
      Title: TCP14 and TCP15 mediate the promotion of seed germination by gibberellins in Arabidopsis thaliana.
    Submit: New GeneRIF Correction See all GeneRIFs (15)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105637.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA endoreduplication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell division IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within gynoecium development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within inflorescence development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular auxin homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of anthocyanin biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cytokinin IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within stamen filament development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TCP family transcription factor
    NP_564973.1
    • TCP family transcription factor; FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TEOSINTE BRANCHED, cycloidea and PCF (TCP) 14 (TAIR:AT3G47620.1); Has 863 Blast hits to 861 proteins in 131 species: Archae - 0; Bacteria - 6; Metazoa - 120; Fungi - 15; Plants - 698; Viruses - 0; Other Eukaryotes - 24 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26216009..26218071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105637.3 → NP_564973.1  TCP family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564973.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C9L2
      UniProtKB/TrEMBL
      A0A178WLV7, A0A5S9WTD8
      Conserved Domains (1) summary
      pfam03634
      Location:50 → 121
      TCP; TCP family transcription factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C9L2.1

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