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    Toll-Interleukin-Resistance (TIR) domain family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814859, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Toll-Interleukin-Resistance (TIR) domain family protein
    Primary source
    TAIR:AT2G03300
    Locus tag
    AT2G03300
    See related
    Araport:AT2G03300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T4M8.27; T4M8_27
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (1003468..1004222, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene emp24/gp25L/p24 family/GOLD family protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Misexpression of AtTX12 encoding a Toll/interleukin-1 receptor domain induces growth defects and expression of defense-related genes partially independently of EDS1 in Arabidopsis. Song SK. BMB Rep, 2016 Dec. PMID 27802841, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of cellular defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with plasmodesma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Toll-Interleukin-Resistance (TIR) domain family protein
    NP_178429.1
    • Toll-Interleukin-Resistance (TIR) domain family protein; FUNCTIONS IN: transmembrane receptor activity; INVOLVED IN: signal transduction, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Toll-Interleukin-Resistance (TIR) domain family protein (TAIR:AT2G03030.1); Has 1602 Blast hits to 1537 proteins in 50 species: Archae - 0; Bacteria - 3; Metazoa - 0; Fungi - 0; Plants - 1599; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1003468..1004222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126381.1 → NP_178429.1  Toll-Interleukin-Resistance (TIR) domain family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178429.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E551, Q9SKM4
      Conserved Domains (1) summary
      pfam01582
      Location:8 → 164
      TIR; TIR domain
    Nucleotide Protein
    Heading Accession and Version

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