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    pruR proline utilization regulator [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880836, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pruR
    Gene description
    proline utilization regulator
    Locus tag
    PA0780
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (848383..849135)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene inhibitor of cysteine peptidase Neighboring gene ATP-dependent protease Neighboring gene hypothetical protein Neighboring gene bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Divergent structure and regulatory mechanism of proline catabolic systems: characterization of the putAP proline catabolic operon of Pseudomonas aeruginosa PAO1 and its regulation by PruR, an AraC/XylS family protein. Nakada Y, et al. J Bacteriol, 2002 Oct. PMID 12270821, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of proline catabolic process to glutamate IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proline utilization regulator
    NP_249471.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      848383..849135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_249471.1 proline utilization regulator [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_249471.1

      Status: PROVISIONAL

      Conserved Domains (2) summary
      COG2207
      Location:131 → 249
      AraC; AraC-type DNA-binding domain and AraC-containing proteins [Transcription]
      cl40423
      Location:6 → 72
      cupin_RmlC-like; RmlC-like cupin superfamily
    Nucleotide Protein
    Heading Accession and Version

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