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    PA4078 nonribosomal peptide synthetase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878689, updated on 24-Aug-2024

    Summary

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    Gene symbol
    PA4078
    Gene description
    nonribosomal peptide synthetase
    Locus tag
    PA4078
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4555254..4558229)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene transcriptional regulator Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator Neighboring gene short-chain dehydrogenase Neighboring gene response regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa. Hong Z, et al. Angew Chem Int Ed Engl, 2019 Mar 4. PMID 30548135
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa.
      Title: Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    nonribosomal peptide synthetase
    NP_252767.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4555254..4558229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252767.1 nonribosomal peptide synthetase [Pseudomonas aeruginosa PAO1]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HWV0
      Conserved Domains (3) summary
      TIGR01746
      Location:620 → 990
      Thioester-redct; thioester reductase domain
      cd17651
      Location:10 → 489
      A_NRPS_VisG_like; similar to adenylation domain of virginiamycin S synthetase
      pfam00550
      Location:517 → 570
      PP-binding; Phosphopantetheine attachment site
    Nucleotide Protein
    Heading Accession and Version

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