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    Fam53c family with sequence similarity 53, member C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685405, updated on 27-Nov-2024

    Summary

    Official Symbol
    Fam53cprovided by RGD
    Official Full Name
    family with sequence similarity 53, member Cprovided by RGD
    Primary source
    RGD:1593851
    See related
    EnsemblRapid:ENSRNOG00000020261 AllianceGenome:RGD:1593851
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in protein import into nucleus. Predicted to be active in nucleus. Orthologous to human FAM53C (family with sequence similarity 53 member C). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 73.9), Adrenal (RPKM 73.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fam53c in Genome Data Viewer
    Location:
    18p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (26638781..26652294)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (26364050..26378173)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (27558094..27572633)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 25C Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC108348765 Neighboring gene stem-loop binding protein like Neighboring gene lysine demethylase 3B Neighboring gene receptor accessory protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427416.1NP_001414345.1  protein FAM53C

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      D3ZH55
      Related
      ENSRNOP00000027499.2, ENSRNOT00000027499.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      26638781..26652294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277591.1XP_063133661.1  protein FAM53C isoform X1

      UniProtKB/TrEMBL
      A0A8I6A450