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    Plet1 placenta expressed transcript 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363060, updated on 9-Dec-2024

    Summary

    Official Symbol
    Plet1provided by RGD
    Official Full Name
    placenta expressed transcript 1provided by RGD
    Primary source
    RGD:1359217
    See related
    EnsemblRapid:ENSRNOG00000024346 AllianceGenome:RGD:1359217
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of cell-matrix adhesion; positive regulation of cell migration; and wound healing, spreading of epidermal cells. Predicted to be located in membrane. Predicted to be active in apical plasma membrane and external side of plasma membrane. Orthologous to human PLET1 (placenta expressed transcript 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 399.3), Testes (RPKM 349.0) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Plet1 in Genome Data Viewer
    Location:
    8q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (59738639..59750062)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (50842242..50853666)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (54925624..54937068)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094147 Neighboring gene phosphoglycerate mutase 1, pseudogene 13 Neighboring gene 6-pyruvoyl-tetrahydropterin synthase Neighboring gene beta-carotene oxygenase 2 Neighboring gene interleukin 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cell-matrix adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell-matrix adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell migration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in wound healing, spreading of epidermal cells IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in wound healing, spreading of epidermal cells ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in wound healing, spreading of epidermal cells ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    placenta-expressed transcript 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014209.2NP_001014231.1  placenta-expressed transcript 1 protein isoform 1 precursor

      See identical proteins and their annotated locations for NP_001014231.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q5HZW7
      UniProtKB/TrEMBL
      A0A8L2QTA5
      Related
      ENSRNOP00000055980.4, ENSRNOT00000059210.6
    2. NM_001393867.1NP_001380796.1  placenta-expressed transcript 1 protein isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8L2QTA5, A6J4D2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      59738639..59750062
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)