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    Dipk1b divergent protein kinase domain 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dipk1bprovided by RGD
    Official Full Name
    divergent protein kinase domain 1Bprovided by RGD
    Primary source
    RGD:1308600
    See related
    EnsemblRapid:ENSRNOG00000004532 AllianceGenome:RGD:1308600
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PIP49; Fam69b; RGD1308600
    Summary
    Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DIPK1B (divergent protein kinase domain 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 184.2), Heart (RPKM 67.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dipk1b in Genome Data Viewer
    Location:
    3p13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (29852710..29862248)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (9455914..9464169)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (4083797..4091550)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene EGF-like-domain, multiple 7 Neighboring gene microRNA 126a Neighboring gene microRNA 126b Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene uncharacterized LOC100911266 Neighboring gene small nucleolar RNA SNORA43 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC109181

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    divergent protein kinase domain 1B
    Names
    family with sequence similarity 69, member B
    pancreatitis-induced protein 49
    protein FAM69B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014178.2 → NP_001014200.2  divergent protein kinase domain 1B

      See identical proteins and their annotated locations for NP_001014200.2

      Status: VALIDATED

      Source sequence(s)
      AI070071, CA504820, EV771144
      UniProtKB/Swiss-Prot
      Q5FVL3
      UniProtKB/TrEMBL
      A0A8I6GMA2, A6JTG7
      Related
      ENSRNOP00000097936.2, ENSRNOT00000104117.2
      Conserved Domains (2) summary
      pfam12260
      Location:197 → 399
      PIP49_C; Protein-kinase domain of FAM69
      pfam14875
      Location:23 → 179
      PIP49_N; N-term cysteine-rich ER, FAM69

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      29852710..29862248
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105361.2 → XP_038961289.1  divergent protein kinase domain 1B isoform X2

      UniProtKB/TrEMBL
      A0A8I6GMA2
      Conserved Domains (2) summary
      pfam12260
      Location:155 → 347
      PIP49_C; Protein-kinase domain of FAM69
      pfam14875
      Location:23 → 163
      PIP49_N; N-term cysteine-rich ER, FAM69

    2. XM_039105360.2 → XP_038961288.1  divergent protein kinase domain 1B isoform X1

      UniProtKB/TrEMBL
      A0A8I6GMA2
      Conserved Domains (2) summary
      pfam12260
      Location:194 → 396
      PIP49_C; Protein-kinase domain of FAM69
      pfam14875
      Location:23 → 176
      PIP49_N; N-term cysteine-rich ER, FAM69
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVL3.2 GenPept UniProtKB/Swiss-Prot:Q5FVL3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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