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    Synpr synaptoporin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 66030, updated on 9-Dec-2024

    Summary

    Official Symbol
    Synprprovided by RGD
    Official Full Name
    synaptoporinprovided by RGD
    Primary source
    RGD:708366
    See related
    EnsemblRapid:ENSRNOG00000008203 AllianceGenome:RGD:708366
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Involved in modulation of chemical synaptic transmission. Is active in hippocampal mossy fiber to CA3 synapse and synaptic vesicle membrane. Orthologous to human SYNPR (synaptoporin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 382.0) See more
    Orthologs
    NEW
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    Genomic context

    See Synpr in Genome Data Viewer
    Location:
    15p16-p15
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (14003861..14330808, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (11573373..11900255, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (14558613..14885790, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene sentan, cilia apical structure protein Neighboring gene ribosomal protein S20, pseudogene 5 Neighboring gene uncharacterized LOC102552767 Neighboring gene ornithine decarboxylase antizyme 1, pseudogene 2 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene calcium dependent secretion activator Neighboring gene Histone deacetylase 1, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    synaptoporin
    Names
    synaptorin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023974.1NP_076464.1  synaptoporin precursor

      See identical proteins and their annotated locations for NP_076464.1

      Status: PROVISIONAL

      Source sequence(s)
      AF306459
      UniProtKB/Swiss-Prot
      P22831, Q9ERH1
      UniProtKB/TrEMBL
      A0A0G2K1H2, A6K083
      Related
      ENSRNOP00000011307.3, ENSRNOT00000011307.7
      Conserved Domains (1) summary
      pfam01284
      Location:69196
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      14003861..14330808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093644.2XP_038949572.1  synaptoporin isoform X2

      UniProtKB/TrEMBL
      A0A0G2K1H2, A0A8I5ZK40, A6K082
      Related
      ENSRNOP00000076574.2, ENSRNOT00000100360.2
      Conserved Domains (1) summary
      pfam01284
      Location:15216
      MARVEL; Membrane-associating domain
    2. XM_063274618.1XP_063130688.1  synaptoporin isoform X1

      UniProtKB/TrEMBL
      A0A0G2K1H2
      Related
      ENSRNOP00000106750.1, ENSRNOT00000127244.1