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    Mycbpap MYCBP associated protein [ Mus musculus (house mouse) ]

    Gene ID: 104601, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Mycbpapprovided by MGI
    Official Full Name
    MYCBP associated proteinprovided by MGI
    Primary source
    MGI:MGI:2388726
    See related
    Ensembl:ENSMUSG00000039110 AllianceGenome:MGI:2388726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AMAM-1; AMAP-1; 4932408B01Rik
    Summary
    Predicted to be involved in chemical synaptic transmission and spermatogenesis. Predicted to be located in cytoplasm. Is expressed in 4th ventricle lateral recess; choroid plexus; lateral ventricle choroid plexus; and pancreas epithelium. Orthologous to human MYCBPAP (MYCBP associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 46.8) and lung adult (RPKM 2.1) See more
    Orthologs
    human all
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    Genomic context

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    See Mycbpap in Genome Data Viewer
    Location:
    11 D; 11 58.9 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94392173..94423219, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94501347..94532386, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3 Neighboring gene predicted gene, 51873 Neighboring gene predicted gene, 35650 Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. Yukitake H, et al. Biochim Biophys Acta, 2002 Aug 19. PMID 12151104
    2. The sperm-associated antigen 6 interactome and its role in spermatogenesis. Liu Y, et al. Reproduction, 2019 Aug. PMID 31146259, Free PMC Article
    3. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. differential gene expression of AMAP-1 during the course of spermatogenesis (AMAP-1)
      Title: AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chemical synaptic transmission ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MYCBP-associated protein
    Names
    AMY-1-binding protein 1
    AMY1-associating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001415760.1 → NP_001402689.1  MYCBP-associated protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL645809
      UniProtKB/Swiss-Prot
      Q5SUV2, Q80YS8, Q8R2Q9
      UniProtKB/TrEMBL
      A0A668KL73
      Related
      ENSMUSP00000159222.2, ENSMUST00000239238.2

    2. NM_170671.3 → NP_733771.3  MYCBP-associated protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL645809
      Consensus CDS
      CCDS48887.1
      UniProtKB/Swiss-Prot
      Q5SUV2, Q80YS8, Q8R2Q9
      Related
      ENSMUSP00000091477.4, ENSMUST00000093945.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      94392173..94423219 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531938.5 → XP_006532001.1  MYCBP-associated protein isoform X1

      UniProtKB/Swiss-Prot
      Q5SUV2, Q80YS8, Q8R2Q9
      Conserved Domains (1) summary
      pfam14646
      Location:241 → 658
      MYCBPAP; MYCBP-associated protein family

    2. XM_006531939.4 → XP_006532002.1  MYCBP-associated protein isoform X2

      UniProtKB/Swiss-Prot
      Q5SUV2, Q80YS8, Q8R2Q9
      Conserved Domains (1) summary
      pfam14646
      Location:241 → 658
      MYCBPAP; MYCBP-associated protein family

    RNA

    1. XR_388315.4 RNA Sequence

    2. XR_003949210.2 RNA Sequence

      Related
      ENSMUST00000123496.8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5SUV2.1 GenPept UniProtKB/Swiss-Prot:Q5SUV2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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