htk hat-trick [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: htkprovided by FlyBase
Official Full Name: hat-trickprovided by FlyBase
Primary source: FLYBASE:FBgn0085451
Locus tag: Dmel_CG34422
See related: AllianceGenome:FB:FBgn0085451
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ARID4B; CG34422; CG7274; CG7282; Dmel\CG34422; Htk; Q9VWP3_DROME
Old locus tag: CG7274; CG7282; Dmel_CG7274; Dmel_CG7282
Summary: Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coregulator binding activity. Involved in positive regulation of Notch signaling pathway and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of Sin3-type complex. Is expressed in several structures, including adult brain cell body rind; anterior endoderm; anterior endoderm anlage; central brain primordium; and ganglia. Orthologous to human ARID4A (AT-rich interaction domain 4A) and ARID4B (AT-rich interaction domain 4B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (18843663..18855858)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (18737696..18749891)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor binding	IPI Inferred from Physical Interaction more info	PubMed
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription cis-regulatory region binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of Notch signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of Sin3-type complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	HDA more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

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