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    Nxpe2 neurexophilin and PC-esterase domain family, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 78252, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nxpe2provided by MGI
    Official Full Name
    neurexophilin and PC-esterase domain family, member 2provided by MGI
    Primary source
    MGI:MGI:1925502
    See related
    Ensembl:ENSMUSG00000032028 AllianceGenome:MGI:1925502
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam55b; 4432416J03Rik
    Summary
    Predicted to be located in membrane. Is expressed in several structures, including ganglia; limb; pituitary gland; sensory organ; and skeletal musculature. Orthologous to human NXPE2 (neurexophilin and PC-esterase domain family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver E14 (RPKM 35.9), liver E14.5 (RPKM 33.4) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Nxpe2 in Genome Data Viewer
    Location:
    9 A5.3; 9 26.38 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (48229303..48264749, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (48318003..48353449, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene neurexophilin and PC-esterase domain family, member 4 Neighboring gene predicted gene, 57543 Neighboring gene STARR-positive B cell enhancer mm9_chr9:48025608-48025909 Neighboring gene predicted gene, 51672 Neighboring gene STARR-seq mESC enhancer starr_24065 Neighboring gene neurexophilin and PC-esterase domain family, member 1, pseudogene Neighboring gene predicted gene, 32131 Neighboring gene NHP2 non-histone chromosome protein 2-like 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NXPE family member 2
    Names
    family with sequence similarity 55, member B
    protein FAM55B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428899.1NP_001415828.1  NXPE family member 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154373
      UniProtKB/Swiss-Prot
      B2RU41, Q3U095, Q8BM95, Q9CX72
    2. NM_001428900.1NP_001415829.1  NXPE family member 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154373
      UniProtKB/Swiss-Prot
      B2RU41, Q3U095, Q8BM95, Q9CX72
    3. NM_030069.4NP_084345.2  NXPE family member 2 isoform 1

      See identical proteins and their annotated locations for NP_084345.2

      Status: VALIDATED

      Source sequence(s)
      AC154373
      Consensus CDS
      CCDS23151.1
      UniProtKB/Swiss-Prot
      B2RU41, Q3U095, Q8BM95, Q9CX72
      UniProtKB/TrEMBL
      A0A0R4J0E5
      Related
      ENSMUSP00000034527.8, ENSMUST00000034527.14
      Conserved Domains (1) summary
      pfam06312
      Location:141269
      Neurexophilin; Neurexophilin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      48229303..48264749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313695.3XP_017169184.1  NXPE family member 2 isoform X1

      UniProtKB/Swiss-Prot
      B2RU41, Q3U095, Q8BM95, Q9CX72
      Conserved Domains (1) summary
      pfam06312
      Location:142270
      Neurexophilin
    2. XM_006510693.4XP_006510756.1  NXPE family member 2 isoform X2

      UniProtKB/Swiss-Prot
      B2RU41, Q3U095, Q8BM95, Q9CX72
      Conserved Domains (1) summary
      pfam06312
      Location:141269
      Neurexophilin
    3. XM_006510694.4XP_006510757.1  NXPE family member 2 isoform X3

      Conserved Domains (1) summary
      pfam06312
      Location:96224
      Neurexophilin
    4. XM_017313696.3XP_017169185.1  NXPE family member 2 isoform X4

      Conserved Domains (1) summary
      pfam06312
      Location:142270
      Neurexophilin
    5. XM_006510696.4XP_006510759.1  NXPE family member 2 isoform X5

      Conserved Domains (1) summary
      pfam06312
      Location:141269
      Neurexophilin