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    Tigd3 tigger transposable element derived 3 [ Mus musculus (house mouse) ]

    Gene ID: 332359, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tigd3provided by MGI
    Official Full Name
    tigger transposable element derived 3provided by MGI
    Primary source
    MGI:MGI:2681860
    See related
    Ensembl:ENSMUSG00000044390 AllianceGenome:MGI:2681860
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA binding activity. Predicted to be active in nucleus. Orthologous to human TIGD3 (tigger transposable element derived 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E14 (RPKM 3.2), whole brain E14.5 (RPKM 3.1) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tigd3 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5941166..5944156, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5891138..5894128, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_45411 Neighboring gene FERM domain containing 8, opposite strand Neighboring gene FERM domain containing 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5878208-5878317 Neighboring gene solute carrier family 25, member 45 Neighboring gene STARR-positive B cell enhancer ABC_E1522 Neighboring gene double PHD fingers 2 Neighboring gene STARR-positive B cell enhancer ABC_E7628 Neighboring gene predicted gene, 42067

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC60957, MGC67569

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tigger transposable element-derived protein 3
    Names
    tigger transposable element derived 3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362045.1 → NP_001348974.1  tigger transposable element-derived protein 3

      Status: VALIDATED

      Source sequence(s)
      AC142098
      Consensus CDS
      CCDS29483.1
      UniProtKB/Swiss-Prot
      Q7TM95
      Related
      ENSMUSP00000157880.2, ENSMUST00000236767.2
      Conserved Domains (3) summary
      pfam03221
      Location:76 → 133
      HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
      cl21459
      Location:6 → 57
      HTH; Helix-turn-helix domains
      cl21549
      Location:193 → 360
      rve; Integrase core domain

    2. NM_198634.2 → NP_941036.1  tigger transposable element-derived protein 3

      See identical proteins and their annotated locations for NP_941036.1

      Status: VALIDATED

      Source sequence(s)
      AC142098, BC055784, BQ558865
      Consensus CDS
      CCDS29483.1
      UniProtKB/Swiss-Prot
      Q7TM95
      Related
      ENSMUSP00000059302.5, ENSMUST00000055911.6
      Conserved Domains (3) summary
      pfam03221
      Location:76 → 133
      HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
      cl21459
      Location:6 → 57
      HTH; Helix-turn-helix domains
      cl21549
      Location:193 → 360
      rve; Integrase core domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5941166..5944156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TM95.1 GenPept UniProtKB/Swiss-Prot:Q7TM95

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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