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    Zfp385c zinc finger protein 385C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303537, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp385cprovided by RGD
    Official Full Name
    zinc finger protein 385Cprovided by RGD
    Primary source
    RGD:1563442
    See related
    EnsemblRapid:ENSRNOG00000025370 AllianceGenome:RGD:1563442
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563442
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be active in nucleus. Orthologous to human ZNF385C (zinc finger protein 385C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 38.1), Heart (RPKM 27.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp385c in Genome Data Viewer
    Location:
    10q31
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (86062329..86118454, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (85562003..85618100, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (88541759..88597058, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras-like 2 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene chromosome 10 C17orf113 homolog pseudogene Neighboring gene uncharacterized LOC120095293 Neighboring gene DEXH-box helicase 58 Neighboring gene lysine acetyltransferase 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 385C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430202.1 → NP_001417131.1  zinc finger protein 385C isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      B1WC87

    2. NM_001430203.1 → NP_001417132.1  zinc finger protein 385C isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      B1WC87

    3. NM_001430204.1 → NP_001417133.1  zinc finger protein 385C isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      B1WC87

    4. NM_001430205.1 → NP_001417134.1  zinc finger protein 385C isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      B1WC87

    5. NM_001430206.1 → NP_001417135.1  zinc finger protein 385C isoform d

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      D3ZE95

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      86062329..86118454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270150.1 → XP_063126220.1  zinc finger protein 385C isoform X3

      Related
      ENSRNOP00000107029.1, ENSRNOT00000135407.1

    2. XM_039087740.2 → XP_038943668.1  zinc finger protein 385C isoform X3

      UniProtKB/TrEMBL
      B1WC87
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:7 → 305
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:304 → 372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:371 → 395
      zf-met; Zinc-finger of C2H2 type

    3. XM_039087739.2 → XP_038943667.1  zinc finger protein 385C isoform X2

      UniProtKB/TrEMBL
      B1WC87
      Conserved Domains (3) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:303 → 371
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:370 → 394
      zf-met; Zinc-finger of C2H2 type

    4. XM_063270148.1 → XP_063126218.1  zinc finger protein 385C isoform X1

    5. XM_039087736.2 → XP_038943664.1  zinc finger protein 385C isoform X1

      UniProtKB/TrEMBL
      B1WC87
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:7 → 305
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:304 → 372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:371 → 395
      zf-met; Zinc-finger of C2H2 type

    6. XM_063270151.1 → XP_063126221.1  zinc finger protein 385C isoform X4

      Related
      ENSRNOP00000031848.6, ENSRNOT00000032737.8

    7. XM_039087737.2 → XP_038943665.1  zinc finger protein 385C isoform X1

      UniProtKB/TrEMBL
      B1WC87
      Related
      ENSRNOP00000109629.1, ENSRNOT00000141671.1
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:7 → 305
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:304 → 372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:371 → 395
      zf-met; Zinc-finger of C2H2 type

    8. XM_063270149.1 → XP_063126219.1  zinc finger protein 385C isoform X2

    9. XM_006247466.5 → XP_006247528.1  zinc finger protein 385C isoform X1

      Related
      ENSRNOP00000110435.1, ENSRNOT00000150987.1
      Conserved Domains (4) summary
      smart00451
      Location:45 → 74
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:7 → 305
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:304 → 372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12874
      Location:371 → 395
      zf-met; Zinc-finger of C2H2 type
    Nucleotide Protein Strain
    Heading Accession and Version

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