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    Ntpcr nucleoside-triphosphatase, cancer-related [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361443, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ntpcrprovided by RGD
    Official Full Name
    nucleoside-triphosphatase, cancer-relatedprovided by RGD
    Primary source
    RGD:1306192
    See related
    EnsemblRapid:ENSRNOG00000019922 AllianceGenome:RGD:1306192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306192
    Summary
    Predicted to enable ribonucleoside triphosphate phosphatase activity. Predicted to be located in mitochondrion. Orthologous to human NTPCR (nucleoside-triphosphatase, cancer-related). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 280.0), Muscle (RPKM 145.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ntpcr in Genome Data Viewer
    Location:
    19q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (70598816..70612580)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (53701496..53715260)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (58565576..58579276)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098601 Neighboring gene microtubule-associated protein 10 Neighboring gene pecanex 2 Neighboring gene involucrin-like Neighboring gene uncharacterized LOC120098634

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mapping the in vitro interactome of cardiac sodium (Na(+) )-calcium (Ca(2+) ) exchanger 1 (NCX1). Lubelwana Hafver T, et al. Proteomics, 2017 Sep. PMID 28755400
    2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    4. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    5. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribonucleoside triphosphate phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cancer-related nucleoside-triphosphatase
    Names
    nucleoside-triphosphatase C1orf57 homolog
    NP_001128045.1
    XP_038953830.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134573.1 → NP_001128045.1  cancer-related nucleoside-triphosphatase

      See identical proteins and their annotated locations for NP_001128045.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474054
      UniProtKB/TrEMBL
      A0A8I6A3A7, A6KJ39
      Related
      ENSRNOP00000105264.1, ENSRNOT00000141375.1
      Conserved Domains (2) summary
      smart00382
      Location:5 → 61
      AAA; ATPases associated with a variety of cellular activities
      pfam03266
      Location:6 → 184
      NTPase_1; NTPase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      70598816..70612580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097902.2 → XP_038953830.1  cancer-related nucleoside-triphosphatase isoform X1

      Conserved Domains (1) summary
      cl38936
      Location:24 → 130
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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