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    Ccdc25 coiled-coil domain containing 25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361059, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ccdc25provided by RGD
    Official Full Name
    coiled-coil domain containing 25provided by RGD
    Primary source
    RGD:1307689
    See related
    EnsemblRapid:ENSRNOG00000015939 AllianceGenome:RGD:1307689
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307689
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of cell motility. Predicted to be located in endomembrane system and plasma membrane. Orthologous to human CCDC25 (coiled-coil domain containing 25). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 52.1), Muscle (RPKM 50.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ccdc25 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (44230927..44263317)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (40055368..40087758)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (42522108..42555318)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482136 Neighboring gene PDZ binding kinase Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene NOP53 ribosome biogenesis factor, pseudogene 1 Neighboring gene uncharacterized LOC134482135 Neighboring gene scavenger receptor class A, member 3 Neighboring gene clusterin

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of cell motility ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endomembrane system ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108382.1NP_001101852.1  coiled-coil domain-containing protein 25

      See identical proteins and their annotated locations for NP_001101852.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474023
      UniProtKB/TrEMBL
      A6K6K7, D4AAU6
      Related
      ENSRNOP00000021621.5, ENSRNOT00000021621.7
      Conserved Domains (1) summary
      pfam05670
      Location:1112
      DUF814; Domain of unknown function (DUF814)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      44230927..44263317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274429.1XP_063130499.1  coiled-coil domain-containing protein 25 isoform X1