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    Qng1 Q-nucleotide N-glycosylase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361201, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Qng1provided by RGD
    Official Full Name
    Q-nucleotide N-glycosylase 1provided by RGD
    Primary source
    RGD:1311345
    See related
    EnsemblRapid:ENSRNOG00000019232 AllianceGenome:RGD:1311345
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311345
    Summary
    Predicted to enable hydrolase activity. Predicted to be involved in nucleoside salvage and tRNA-guanine transglycosylation. Orthologous to human QNG1 (Q-nucleotide N-glycosylase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 211.5), Liver (RPKM 134.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Qng1 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (6286801..6294400)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (6281377..6288976)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (6683152..6690724)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene RecQ mediated genome instability 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K Neighboring gene microRNA 7-1 Neighboring gene kinesin family member 27 like 1 Neighboring gene kinesin family member 27 Neighboring gene uncharacterized LOC134482805 Neighboring gene G kinase anchoring protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112925

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleoside salvage ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in tRNA-guanine transglycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    queuosine 5'-phosphate N-glycosylase/hydrolase
    Names
    UPF0553 protein C9orf64 homolog
    NP_001166907.1
    XP_038951776.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173436.3 → NP_001166907.1  queuosine 5'-phosphate N-glycosylase/hydrolase

      See identical proteins and their annotated locations for NP_001166907.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6KAK3, F7FM32
      Related
      ENSRNOP00000057961.3, ENSRNOT00000061249.5
      Conserved Domains (1) summary
      pfam10343
      Location:55 → 338
      Q_salvage; Potential Queuosine, Q, salvage protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      6286801..6294400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095848.2 → XP_038951776.1  queuosine 5'-phosphate N-glycosylase/hydrolase isoform X1

      Conserved Domains (1) summary
      pfam10343
      Location:55 → 201
      Q_salvage; Potential Queuosine, Q, salvage protein family
    Nucleotide Protein Strain
    Heading Accession and Version

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