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    Rnf44 ring finger protein 44 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361212, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rnf44provided by RGD
    Official Full Name
    ring finger protein 44provided by RGD
    Primary source
    RGD:1307212
    See related
    EnsemblRapid:ENSRNOG00000017641 AllianceGenome:RGD:1307212
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Orthologous to human RNF44 (ring finger protein 44). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 72.9), Spleen (RPKM 64.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf44 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (9925100..9939496)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9919982..9934376)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (10458036..10472410)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene G protein-regulated inducer of neurite outgrowth 1 Neighboring gene cadherin-related family member 2 Neighboring gene Fas associated factor family member 2 Neighboring gene clathrin, light chain B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024795.1 → NP_001019966.1  RING finger protein 44

      See identical proteins and their annotated locations for NP_001019966.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098030
      UniProtKB/Swiss-Prot
      Q4V7B8
      UniProtKB/TrEMBL
      A0A8I6ANS6, A6KAX7
      Related
      ENSRNOP00000057548.5, ENSRNOT00000060822.5
      Conserved Domains (1) summary
      pfam13639
      Location:298 → 339
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      9925100..9939496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253634.5 → XP_006253696.1  RING finger protein 44 isoform X1

      See identical proteins and their annotated locations for XP_006253696.1

      UniProtKB/TrEMBL
      A0A0G2JTM4
      Conserved Domains (1) summary
      pfam13639
      Location:381 → 422
      zf-RING_2; Ring finger domain

    2. XM_017600594.3 → XP_017456083.1  RING finger protein 44 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ANS6
      Conserved Domains (1) summary
      pfam13639
      Location:380 → 421
      zf-RING_2; Ring finger domain

    3. XM_006253633.5 → XP_006253695.1  RING finger protein 44 isoform X1

      See identical proteins and their annotated locations for XP_006253695.1

      UniProtKB/TrEMBL
      A0A0G2JTM4
      Conserved Domains (1) summary
      pfam13639
      Location:381 → 422
      zf-RING_2; Ring finger domain

    4. XM_063276556.1 → XP_063132626.1  RING finger protein 44 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ANS6

    5. XM_006253637.5 → XP_006253699.1  RING finger protein 44 isoform X1

      See identical proteins and their annotated locations for XP_006253699.1

      UniProtKB/TrEMBL
      A0A0G2JTM4
      Conserved Domains (1) summary
      pfam13639
      Location:381 → 422
      zf-RING_2; Ring finger domain

    6. XM_063276555.1 → XP_063132625.1  RING finger protein 44 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JTM4

    7. XM_017600593.3 → XP_017456082.1  RING finger protein 44 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JTM4
      Conserved Domains (1) summary
      pfam13639
      Location:381 → 422
      zf-RING_2; Ring finger domain

    8. XM_039095850.2 → XP_038951778.1  RING finger protein 44 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JTM4, A0A8L2QTU2
      Related
      ENSRNOP00000068768.3, ENSRNOT00000089885.3
      Conserved Domains (1) summary
      cd16472
      Location:296 → 340
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins

    9. XM_006253644.5 → XP_006253706.1  RING finger protein 44 isoform X3

      See identical proteins and their annotated locations for XP_006253706.1

      UniProtKB/TrEMBL
      A0A0G2JTM4, A0A8L2QTU2
      Conserved Domains (1) summary
      cd16472
      Location:296 → 340
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V7B8.1 GenPept UniProtKB/Swiss-Prot:Q4V7B8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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