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    C18h18orf32 similar to human chromosome 18 open reading frame 32 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498886, updated on 27-Nov-2024

    Summary

    Official Symbol
    C18h18orf32provided by RGD
    Official Full Name
    similar to human chromosome 18 open reading frame 32provided by RGD
    Primary source
    RGD:1562987
    See related
    EnsemblRapid:ENSRNOG00000018676 AllianceGenome:RGD:1562987
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562987
    Summary
    Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in endoplasmic reticulum and lipid droplet. Orthologous to human C18orf32 (chromosome 18 open reading frame 32). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 428.4), Brain (RPKM 401.8) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See C18h18orf32 in Genome Data Viewer
    Location:
    18q12.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (70861434..70869983)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (68586278..68594851)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (70974885..70983362)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD58 Neighboring gene small nucleolar RNA SNORD58 Neighboring gene ribosomal protein L17 Neighboring gene U6 spliceosomal RNA Neighboring gene dymeclin Neighboring gene uncharacterized LOC134482962

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of canonical NF-kappaB signal transduction ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in lipid droplet ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lipid droplet ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    UPF0729 protein C18orf32 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173472.1NP_001166943.1  UPF0729 protein C18orf32 homolog

      See identical proteins and their annotated locations for NP_001166943.1

      Status: VALIDATED

      Source sequence(s)
      BC162045, CB568734
      UniProtKB/Swiss-Prot
      B1WC88
      Conserved Domains (1) summary
      pfam14975
      Location:238
      DUF4512; Domain of unknown function (DUF4512)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      70861434..70869983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008772163.3XP_008770385.1  UPF0729 protein C18orf32 homolog isoform X1

      See identical proteins and their annotated locations for XP_008770385.1

      UniProtKB/Swiss-Prot
      B1WC88
      Related
      ENSRNOP00000103781.1, ENSRNOT00000025198.7
      Conserved Domains (1) summary
      pfam14975
      Location:238
      DUF4512; Domain of unknown function (DUF4512)