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    Nkg7 natural killer cell granule protein 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171062, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nkg7provided by RGD
    Official Full Name
    natural killer cell granule protein 7provided by RGD
    Primary source
    RGD:621523
    See related
    EnsemblRapid:ENSRNOG00000017749 AllianceGenome:RGD:621523
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in several processes, including CD4-positive, alpha-beta T cell activation; defense response to other organism; and granzyme-mediated programmed cell death signaling pathway. Predicted to be located in cytolytic granule membrane. Predicted to be active in plasma membrane. Orthologous to human NKG7 (natural killer cell granule protein 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 365.0), Lung (RPKM 244.9) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Nkg7 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (102981497..102982564)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (93844748..93845975)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (98492873..98493940, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102550061 Neighboring gene similar to human chromosome 19 open reading frame 84 Neighboring gene lens intrinsic membrane protein 2 Neighboring gene claudin domain containing 2 Neighboring gene electron transfer flavoprotein subunit beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein NKG7
    Names
    natural killer cell group 7 sequence

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133540.1NP_598224.1  protein NKG7

      See identical proteins and their annotated locations for NP_598224.1

      Status: PROVISIONAL

      Source sequence(s)
      AF082535
      UniProtKB/TrEMBL
      A0A8I6AE16, A6JAH6, F7FAL5, Q9WVL9
      Related
      ENSRNOP00000023942.2, ENSRNOT00000023942.7
      Conserved Domains (1) summary
      cl21598
      Location:21141
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      102981497..102982564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)