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    Crip2 cysteine-rich protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 338401, updated on 27-Nov-2024

    Summary

    Official Symbol
    Crip2provided by RGD
    Official Full Name
    cysteine-rich protein 2provided by RGD
    Primary source
    RGD:1302959
    See related
    EnsemblRapid:ENSRNOG00000005041 AllianceGenome:RGD:1302959
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    CRP2
    Summary
    Predicted to enable metal ion binding activity. Predicted to act upstream of or within hemopoiesis and positive regulation of cell population proliferation. Predicted to be located in cell cortex. Orthologous to human CRIP2 (cysteine rich protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 2928.5), Lung (RPKM 985.6) and 5 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Crip2 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (138042175..138047121)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (132221120..132226066)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137953545..137958491)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene metastasis associated 1 Neighboring gene cysteine rich protein 1 Neighboring gene tubulin epsilon and delta complex 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within hemopoiesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cysteine-rich protein 2
    Names
    CRP-2
    LIM/double zinc-finger protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022501.1NP_071946.1  cysteine-rich protein 2

      See identical proteins and their annotated locations for NP_071946.1

      Status: PROVISIONAL

      Source sequence(s)
      D17512
      UniProtKB/Swiss-Prot
      P36201
      UniProtKB/TrEMBL
      A0A8I6A6Z5, A6KBY2
      Related
      ENSRNOP00000006804.3, ENSRNOT00000006804.7
      Conserved Domains (1) summary
      cd09476
      Location:558
      LIM1_TLP; The first LIM domain of thymus LIM protein (TLP)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      138042175..138047121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262035.1XP_063118105.1  cysteine-rich protein 2 isoform X1

      UniProtKB/TrEMBL
      A6KBY6