gtf-2A2 Transcription initiation factor IIA subunit 2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: gtf-2A2
Official Full Name: Transcription initiation factor IIA subunit 2
Primary source: WormBase:WBGene00013736
Locus tag: CELE_Y111B2A.13
See related: AllianceGenome:WB:WBGene00013736
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gtf-2A2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 2

Sequence:: Chromosome: III; NC_003281.10 (12624766..12625897)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS3-205 (e-PCR)
- UniSTS:242051

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables TBP-class protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIA complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIA complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Transcription initiation factor IIA subunit 2

NP_499644.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

12624766..12625897

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067243.7 → NP_499644.1 Transcription initiation factor IIA subunit 2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499644.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9NEX2

Conserved Domains (3) summary

cd10145
Location:5 → 53

TFIIA_gamma_N; Gamma subunit of transcription initiation factor IIA, N-terminal helical domain

COG5123
Location:6 → 105

TOA2; Transcription initiation factor IIA, gamma subunit [Transcription]

pfam02751
Location:55 → 104

TFIIA_gamma_C; Transcription initiation factor IIA, gamma subunit