C01G10.10 putative tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C01G10.10
Official Full Name: putative tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
Primary source: WormBase:WBGene00007237
Locus tag: CELE_C01G10.10
See related: AllianceGenome:WB:WBGene00007237
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be active in mitochondrion. Is expressed in intestine. Orthologous to human OSGEPL1 (O-sialoglycoprotein endopeptidase like 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C01G10.10 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 8

Sequence:: Chromosome: V; NC_003283.11 (15080134..15082441, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The C01G10.10 protein, (Qri7)localizes to the mitochondria and is involved in mitochondrial genome maintenance.
Title: Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C01G10.9 (e-PCR)
- UniSTS:321175

C01G10.10 (e-PCR)
- UniSTS:321176

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables N(6)-L-threonylcarbamoyladenine synthase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in tRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA threonylcarbamoyladenosine modification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

NP_506713.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

15080134..15082441 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074312.7 → NP_506713.1 putative tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506713.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93170

Conserved Domains (2) summary

COG0533
Location:24 → 350

TsaD; tRNA A37 threonylcarbamoyltransferase TsaD [Translation, ribosomal structure and biogenesis]

cl22532
Location:25 → 131

Carbam_trans_N; Carbamoyltransferase N-terminus