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    M106.3 Prostaglandin reductase 2 [ Caenorhabditis elegans ]

    Gene ID: 174671, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M106.3
    Official Full Name
    Prostaglandin reductase 2
    Primary source
    WormBase:WBGene00010911
    Locus tag
    CELE_M106.3
    See related
    AllianceGenome:WB:WBGene00010911
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and vulval muscle. Orthologous to human PTGR2 (prostaglandin reductase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M106.3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (10857442..10860909, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Regulatory protein zeste Neighboring gene DNA-directed RNA polymerase III subunit RPC9 Neighboring gene putative GMP synthase [glutamine-hydrolyzing] Neighboring gene ncRNA Neighboring gene F-actin-capping protein subunit beta Neighboring gene Peptidyl-prolyl cis-trans isomerase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in prostaglandin metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in prostaglandin metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Prostaglandin reductase 2
    NP_001076630.1
    • Confirmed by transcript evidence
    NP_001379459.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10857442..10860909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393183.1 → NP_001379459.1  Prostaglandin reductase 2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0G840
      Conserved Domains (1) summary
      cd08293
      Location:22 → 373
      PTGR2; Prostaglandin reductase

    2. NM_001083161.4 → NP_001076630.1  Prostaglandin reductase 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001076630.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0G839
      Conserved Domains (1) summary
      cd08293
      Location:14 → 365
      PTGR2; Prostaglandin reductase
    Nucleotide Protein
    Heading Accession and Version

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