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    R11G1.1 EGF-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187815, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R11G1.1
    Official Full Name
    EGF-like domain-containing protein
    Primary source
    WormBase:WBGene00020010
    Locus tag
    CELE_R11G1.1
    See related
    AllianceGenome:WB:WBGene00020010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone binding activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to be part of receptor complex. Predicted to be active in apical plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R11G1.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    19
    Sequence:
    Chromosome: X; NC_003284.9 (3659492..3667147)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein snet-1 Neighboring gene BPTI/Kunitz inhibitor domain-containing protein C02F12.5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables low-density lipoprotein particle receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    EGF-like domain-containing protein
    NP_001361923.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3659492..3667147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001374997.2 → NP_001361923.1  EGF-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21948
      Conserved Domains (3) summary
      smart00192
      Location:32 → 64
      LDLa; Low-density lipoprotein receptor domain class A
      PHA03247
      Location:268 → 594
      PHA03247; large tegument protein UL36; Provisional
      cd00112
      Location:113 → 145
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    Nucleotide Protein
    Heading Accession and Version

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