F57B9.1 Putative pyridoxamine 5'-phosphate oxidase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F57B9.1
Official Full Name: Putative pyridoxamine 5'-phosphate oxidase
Primary source: WormBase:WBGene00018996
Locus tag: CELE_F57B9.1
See related: AllianceGenome:WB:WBGene00018996
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable pyridoxamine phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F57B9.1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 4

Sequence:: Chromosome: III; NC_003281.10 (6962340..6963307)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F57B9.1 (e-PCR)
- UniSTS:305650

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables FMN binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables pyridoxamine phosphate oxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables pyridoxamine phosphate oxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in metabolic process	IEA Inferred from Electronic Annotation more info
involved_in organic hydroxy compound metabolic process	IEA Inferred from Electronic Annotation more info
involved_in pyridoxal phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in pyridoxine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in vitamin B6 metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Putative pyridoxamine 5'-phosphate oxidase

NP_001370689.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6962340..6963307

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001382904.2 → NP_001370689.1 Putative pyridoxamine 5'-phosphate oxidase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q20939

Conserved Domains (1) summary

TIGR00558
Location:32 → 226

pdxH; pyridoxamine-phosphate oxidase