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    tct-1 Translationally-controlled tumor protein homolog [ Caenorhabditis elegans ]

    Gene ID: 172944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tct-1
    Official Full Name
    Translationally-controlled tumor protein homolog
    Primary source
    WormBase:WBGene00009122
    Locus tag
    CELE_F25H2.11
    See related
    AllianceGenome:WB:WBGene00009122
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Located in endoplasmic reticulum. Orthologous to several human genes including TPT1 (tumor protein, translationally-controlled 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tct-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (10569112..10569983)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Proteasome subunit alpha type-5 Neighboring gene Large ribosomal subunit protein uL10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Methyltransferase domain-containing protein Neighboring gene Regulator of telomere elongation helicase 1 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the translationally controlled tumour protein in the nematodes Ostertagia ostertagi and Caenorhabditis elegans suggests a pivotal role in egg production. Meyvis Y, et al. Int J Parasitol, 2009 Sep. PMID 19285501
    2. Alternative Poly(A) Tails Meet miRNA Targeting in Caenorhabditis elegans. Khraiwesh B, et al. Genetics, 2017 Jun. PMID 28592507, Free PMC Article
    3. Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Caenorhabditis elegans Somatic Tissues. Blazie SM, et al. Genetics, 2017 Jun. PMID 28348061, Free PMC Article
    4. N-glycosylated intestinal protein BCF-1 shapes microbial colonization by binding bacteria via its fimbrial protein. He Y, et al. Cell Rep, 2023 Jan 31. PMID 36662624
    5. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    Translationally-controlled tumor protein homolog
    NP_001379177.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10569112..10569983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392937.1 → NP_001379177.1  Translationally-controlled tumor protein homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93573
      Conserved Domains (1) summary
      pfam00838
      Location:1 → 175
      TCTP; Translationally controlled tumor protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93573.1

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